Nanotechnology and photodynamic therapy from a clinical perspective

Abstract Photodynamic therapy (PDT) is currently applied clinically in many medical centers worldwide. The clinical outcomes are from one side satisfying and the other highlighting areas of further development. Issues like hydrophobicity photosensitizer (PS), uncontrolled distribution limited tissue penetration accompanying light sources triggered interest research groups. Nanotechnology outstood among various suggested enhancement solutions. In this review, rationale behind using nanotechnology discussed. Light shed on status approval for use. Clinical studies PS‐loaded nanoparticles summarized challenges facing progress those systems enumerated.